Paula’s feedback system is impaired…..

The only clue is a sudden sensation of dysphoria [or unease or distress or , if severe- a sense of anguish] and a sudden inability to perform at baseline level [which results in shame and guilt due to failure to do things like one used to, due to a sudden unspoken amnesia for the task.… Continue reading Paula’s feedback system is impaired…..

Suddenly becoming strange; Paula’s memories are so vivid.

What happened to Paula's mind when she woke up that night feeling anguish and distress is easy and hard to explain. She found out at breakfast with her husband, that she was not herself, she was suddenly strange. Lucky for her part of the strangeness was being silent and non talkative and quiet and reserved,… Continue reading Suddenly becoming strange; Paula’s memories are so vivid.

What is affecting Paula’s memory for self?

Well, we have discussed this for a long time, Paula and I. The brain [and the mind], seems to be more malleable than we realize. At least in the remitting and relapsing syndrome we recognize superficially as bipolar illness or manic depressive insanity [the name Kraepelin gave it]. Dr. Emile Kraepelin's 1926 research findings of… Continue reading What is affecting Paula’s memory for self?

Bipolar Depression may be Respiratory Acidosis

Bipolar depression and mania are serious illnesses that may be caused by acid base disorders due to respiratory pump failure. Arterial blood gas tests and measurement of respiratory rates and depth and minute ventilation are the ways to check out this hypothesis. Disturbed mood, mental status and locomotor activity can occur when ventilation [the motor… Continue reading Bipolar Depression may be Respiratory Acidosis

Manic Depressive Insanity; a dose related effect of alveolar hypoventilation?

Yes! I think that this is a real possibility. Getting an arterial blood gas test for first episode bipolar patients would answer this question. Mild suffocation caused by hypercapnic respiratory failure would explain the distress and anguish described by such patients and would explain the mental fog they experience and the lethargy and psychomotor retardation.… Continue reading Manic Depressive Insanity; a dose related effect of alveolar hypoventilation?

Impaired behavior, mood and mental status of bipolar attacks suggest alveolar hypoventilation.

Alveolar hypoventilation is a laboratory diagnosis. An arterial blood gas test is necessary to detect it. Abnormal respiratory rate, depth and minute ventilation are non invasive and simple ways to see if more invasive arterial blood gas tests are needed. The physiological and biochemical status of the body will be abnormal if the motor act… Continue reading Impaired behavior, mood and mental status of bipolar attacks suggest alveolar hypoventilation.