Uncoupling of breathing from locomotor activity

Abnormal locomotor activity, seen in bipolar illness and delirium may stem from uncoupling of breathing from locomotor activity. This is certainly the case with Paula. And the cause seems to be autonomic nervous system damage at birth or due to early physical trauma. Inhibited motor activity and too slow breathing rate, and too fast-even periodic breathing in the hyper locomotor manic episodes, and mixed states seem to be reactions to PCO2 imbalance due to physical limitations from the uncoupling of breathing.

The patient in distress does not know what is wrong with them. The song Bring Me To Life by Evanescence captures the inner silent agitation and the helplessness that accompanies the inhibited motor activity of depressive insanity due to the involuntary respiratory depression and most likely hypercapnia respiratory failure. It is extremely unpleasant and stressful, yet mysterious and inexplicable.

Bring Me To Life (Synthesis)

Evanescence

How can you see into my eyes, like open doors
Leading you down into my core 
Where I’ve become so numb
Without a soul
My spirit’s sleeping somewhere cold 
Until you find it there and lead it back homeWake me up inside (save me)
Call my name and save me from the dark (wake me up)
Bid my blood to run (I can’t wake up)
Before I come undone (save me)
Save me from the nothing I’ve become, Now that I know what I’m without
You can’t just leave me 
Breathe into me and make me real
Bring me to life, Wake me up inside (save me)
Call my name and save me from the dark (wake me up)
Bid my blood to run (I can’t wake up)
Before I come undone (save me)
Save me from the nothing I’ve become, Bring me to life
I’ve been living a lie
There’s nothing inside
Bring me to life, Frozen inside…

To be continued.

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