Paula’s breathing is Uncoupled from the other vital signs.

Control of Breathing

Andrew M. Dylag MD, Richard J. Martin MD, in Updates on Neonatal Chronic Lung Disease, 2020

Control of Breathing and Physiologic Contributions to Immature Respiratory Control

Respiratory control and its maturation is under tight regulation, with interplay from the central and peripheral nervous systems and feedback from the lung parenchyma and airway musculature. Our still limited knowledge of the normal and pathophysiologic developmental pathways governing the control of breathing comes from both human and animal studies.  Understanding the normal developmental trajectory and maturation of each component coupled with its modification by postnatal environmental factors can inform clinicians about the magnitude of disordered breathing control in preterm and former preterm infants, providing guidelines for monitoring and targets for treatment.

To be continued…..