Well now, that is a very important question. It would certainly explain a lot. It would explain the very recognizable psychomotor retardation, a feature of depression mentioned by observers since antiquity. Psychomotor retardation is a motor sign which is visible to others and the mental slowing is also visible with basic cognitive testing. ........."Psychomotor retardation… Continue reading Is Bipolar Illness a Slowly Progressing Neuromuscular Disorder?
Does Lack of Sleep affect the Skeletal Muscles: in Particular the Respiratory Muscles?
Depression and mania involve serious sleep disturbances . Paula has recently been diagnosed with moderate sleep apnea, [in health] of which she was unaware. Does her sleep apnea get worse when she is "depressed"? We do not know. What we have learnt from a study in France is that ............ "Sleep deprivation can alter endurance… Continue reading Does Lack of Sleep affect the Skeletal Muscles: in Particular the Respiratory Muscles?
Dyspnea or Mood Disorder?
I think that it is impossible to tell the difference using only words. It is especially hard for a patient to know the difference when they do not know the word DYSPNEA and when dyspnea triggers intermittent or ingoing fear and anxiety, sometimes INSTEAD OF the sensation of breathing difficulty. These sensations are intertwined. BUT… Continue reading Dyspnea or Mood Disorder?
When is “sustained”, “unexplained” sensations of fear and distress really the difficult to explain sensation of DYSPNEA?
Dyspnea. Paula always has a mild sensation of dyspnea. Paula thinks that this is normal. [who knows? maybe it is.] Now she has learnt the word for this mild form of discomfort. Dyspnea may be a common distressing symptom but it certainly IS NOT a common word. It is jargon used by doctors that ordinary… Continue reading When is “sustained”, “unexplained” sensations of fear and distress really the difficult to explain sensation of DYSPNEA?
Lack of “normal” Sleep/ Mental Disturbance including Psychosis.
Now this is the kind of science Paula and I are talking about; this could explain why enough sleep deprivation can led to psychosis and other emotional and "mental" disturbances. ....and possible ventilatory failure! "In this issue of the Journal, Rault and colleagues (pp. 976–983) assessed the effect of one night of sleep deprivation on respiratory motor… Continue reading Lack of “normal” Sleep/ Mental Disturbance including Psychosis.
A New Perspective-A Hybrid Approach.
First, all of us need to see bipolar illness and schizophrenia and dementia's as possible consequences of organic dysfunction causing the different and many stages of delirium. Second, we need to realize that "delirium" is relatively common at all ages and it needs to be worked up very carefully and seriously, even though it is… Continue reading A New Perspective-A Hybrid Approach.
Psychosis, Delirium, aren’t they the same thing?
Abstract: Delirium may be a common cause of psychotic symptoms such as hallucinations, bizarre delusions and thought-disorder, even in conditions such as schizophrenia, mania and depression, where delirium has traditionally been excluded by definition. This situation is a consequence of the insensitivity of current clinical criteria for the diagnosis of delirium, which recognize only the… Continue reading Psychosis, Delirium, aren’t they the same thing?
“Severe Sleep Deprivation causes.. a Gradual Progression Toward Psychosis With Increasing Time Awake”
" Long periods without sleep are associated with cognitive difficulties, and can produce psychological symptoms ranging from mood changes to psychotic experiences such as hallucinations (3, 4). .... The interaction between sleep loss and psychotic symptoms has long been known. Historical texts speak of the erstwhile practice of torturing those accused of witchcraft by depriving them… Continue reading “Severe Sleep Deprivation causes.. a Gradual Progression Toward Psychosis With Increasing Time Awake”
Sleep [or, lack of it] in Bipolar Illness
Sleep Disturbance in Bipolar Disorder Across the Lifespan. Harvey AG, Talbot LS, Gershon A. [see the full reference at the end of the section on Summary and Implications.] Abstract: The aim of this article is to highlight the importance of the sleep–wake cycle in children, adolescents, and adults with bipolar disorder. After reviewing the evidence… Continue reading Sleep [or, lack of it] in Bipolar Illness
Metabolism, Mitochondria and Respiratory Rate
If respiratory rate is known to be abnormal at rest at baseline; regularly too slow at rest or regularly too fast at rest or regularly abnormal at rest, it is a BIG deal and it is an important metabolic and physiologic CLUE that must be investigated because of its effects on pH of the blood… Continue reading Metabolism, Mitochondria and Respiratory Rate